A Hybrid Filter and Wrapper Algorithms for Genetic Pathway Analysis of Ovarian Cancer Microarray Dataset
Tsai, Yu-Hung; Tsai, Meng-Hsiun; Kuo, Chung-Yi; Kuo, Ching-Yu (Taiwan)
ABSTRACT:
Ovarian Cancer does not have a high rate of infection among all gynecological cancers; however, it has the highest mortality. A tumor marker CA-125 is used as the tool of screening presently, yet, it lacks accuracy. Finding better screening tools for ovarian cancer is thus a crucial issue. This study aims to create a model capable of identifying the stages of ovarian cancer with Microarray Dataset for its patients and by the Data Mining method, also to identify the Target Genes. The study began by choosing the key genes from the Microarray Dataset for ovarian cancer using a Filter technique which employs ANOVA and Information Gain. The next technique used was a Wrapper, which selects Target Genes from among Important Genes; the Wrapper is mainly used Bio-inspired Algorithms, including BPNN and GA. Our findings suggested that using the optimal identifier of ovarian cancer stages to test on only seven target genes can identify any of the four stages of ovarian cancer with accuracy rate at 94.63%, where the target genes are ITGB2, PLEC, POSTN, C1S, FN1, CDK5 and PAPPA. Such findings can serve as important biological and medical references, which, when testified by biological and medical experiments, are expected to be used as a tool of screening ovarian cancer enabling doctors to diagnose and treat it as early as possible, increasing the survival rate in ovarian cancer patients.
A Study on the Applications and Cases for the Use of the Big Data of Public and Private Sectors
Kim, YongJae (South Korea)
ABSTRACT:
Purpose of this paper aims to analyze the best way to make applications and cases of big data of public and private sectors. Moreover, this paper investigates applications and cases for the utilization of the big data designed for public data. Research methodology of this paper analyzes applications and cases as follows. First, the paper made use of reviewing 2nd data analysis this paper interview focus group Interview and discuss about decision making and practical uses of public sectors. Second, this paper reviewed data analysis and applications and cases of private sectors, especially for the manufacturing industry. Third, Result of this paper founds that it is significant to big data applications and practical uses of marketing and service marketing field. This paper intends to draw conclusion and make implication as follows. Through the above reviews and analysis, we can see the importance of utilization of ICT convergence in various fields which enables to meet required demands not only in manufacturing but also other industries.
A Systems Approach to Designing a Traffic Collision Avoidance Early Warning System
Lamr, Marián; Skrbek, Jan (Czech Republic)
ABSTRACT:
This article examines and evaluates the systems view of the concept of the collision avoidance early warning system (will be referred to as “the early warning system” in all further instances) which uses traffic accident data and data mining algorithms. Principles of the General Systems Theory are used in describing the system and elaborating upon its attributes. Connections to other current telematic systems and its location in the hierarchy of state traffic safety units are discussed steadily and gradually in the article. It also describes the principles of the collision avoidance early warning system, along with its inputs and outputs and the elements and connections it is formed out of. With regard to the principles of the General Systems Theory isomorphism’s are searched for and the feedback and the goals of the system are discussed within.
A Two-Speed Europe in the Area of Research
Geske, Andrejs; Bērziņa, Dina (Latvia)
ABSTRACT:
The world is moving fast and European Union invests significantly into moving towards smart, sustainable and inclusive economy. One of the driving forces for Europe’s advancement is a strong commitment towards the development of knowledge and innovation based economy, supported by relevant European policy initiatives; in particular, research and innovation Framework programmes. The current one, Horizon 2020, promotes excellence in research. Analysing the participation of Member states’ groups (EU-15 and EU-13) to the European Union research Framework programmes and corresponding impact, unequal influence is observed – the dominance of EU-15 country group is obvious. Given the current heterogeneous status of EU-15 and EU-13 countries, such approach increases the disparities between the country groups in terms of involvement into the research projects. Since the Sixth Framework Programme Higher educational institutions (HEI) constitute majority of the Framework programme participants collecting more than 30% of the funding thus determining the scientific progress in Europe. For several Framework programmes in a row the leading higher educational institutions are University of Cambridge and University of Oxford. However, size makes sense – among the top-50 HEI only few universities form Denmark and Sweden can be found, but none from Baltic countries.
Alternative Approach on Meeting Product Demand by an Imperfect EPQ-Based Model and an External Source
Chiu, Yuan-Shyi P.; Chiu, Singa Wang; Jhan, Jia-Hang; Wu, Cheng-Sian (Taiwan)
ABSTRACT:
Meeting product demand by an imperfect economic production quantity (EPQ) model and an additional external source was explored by Chiu et al. [1], using differential calculus approach. This study employs a simplified algebraic method to reexamine such a hybrid EPQ-based replenishment system. As a result, we show that the optimal batch size can be derived without needs
to reference to differential calculus. This straightforward method may assist practitioners or the first year college students, who may be with insufficient knowledge of calculus in understanding the real-life hybrid EPQ-based
replenishment system more effectively.
Assessment of the Factors Influencing Higher Education Funding Policies
Erins, Ingars; Erina, Jana (Latvia)
ABSTRACT:
The aim of this article is to assess the factors that influencing higher education funding policies in Latvia. To achieve the goal, the authors have performed a qualitative and quantitative analysis of scientific literature on factors that influencing higher education funding policies. In order to achieve research results, the authors initially selected higher education funding policy influencing factors based on the European University Association research results (2016), further with the help of data analysis tool NVivo they analyzed scientific articles on the research topic. To obtain empirical data, the authors have developed the questionnaire and adapted it for higher education professionals considering the outlined factors. At the final stage of the research, the data was processed using SPSS: Kaiser-Meyer-Olkin Measure of Sampling Adequacy and Bartlett’s Test of Sphericity, Cronbach’s Alpha, Factor Correlation Matrix, Anti-image Correlation Matrix, Communalities. Assessing the factors influencing higher education funding policies, the authors have come to the conclusion that in total there are 24 factors that can influence higher education funding.
Barriers to Social Innovation and Ways of Overcoming them in Latvia
Oganisjana, Karine; Eremina, Yuliya; Gvatua, Salome; Kabwende, Benjamin Ngongo; Chukwu, Ozoemena Joseph (Latvia)
ABSTRACT:
The paper presents the findings of research conducted to determine the main barriers to social innovation in Latvia and explore the ways they are overcome. The analysis of the qualitative and quantitative data collected while interviewing social innovation projects revealed eight barriers to social innovation. Lack of financing, passivity in the society and administrative and bureaucratic barriers are most frequently faced here. The qualitative content analysis disclosed nine means for overcoming the barriers to social innovation. Three of them: promotional activities, external financial support and external support are most common. Each barrier to social innovation was analyzed also in regard with the means utilized for overcoming it. It showed that there is no universal way to overcome a certain barrier. There could be different combinations of means and actions undertaken. However, the most powerful mean in overcoming barriers to social innovation in Latvia turned out to be promotional activities defined as a set of activities aimed to: educate the society, encourage stakeholders to participate in the project, raise awareness about the topicality of the problem and share information about solutions with the project’s target group.
Bridging the Semantic and Lexical Webs: Concept-Validating and Hypothesis-Exploring Ontologies for the Nexus-PORTAL-DOORS System
Craig, Adam; Bae, Seung-Ho; Taswell, Carl (United States)
ABSTRACT:
The Nexus-PORTAL-DOORS System (NPDS) has been designed with the Hierarchically Distributed Mobile Metadata (HDMM) architectural style to provide
an infrastructure system for managing both lexical and semantic metadata about both virtual and physical entities. We describe here how compatibility
between version 0.9 of the NPDS schema, the new NPDS-interfacing ontologies, and the domain-specific concept-validating hypothesis-exploring ontologies allows NPDS to bootstrap the semantic web onto the more developed lexical web. We then describe how this system will serve as the foundation of a planned platform for automated meta-analysis.
Business Continuity Management System in the Transport
Soušek, Radovan; Rozová, Dana; Němec, Vladimír; Šustr, Martin (Czech Republic)
ABSTRACT:
Continuity of Undertaking in the Transport Companies is an activity which aims at minimizing necessary time to restore the operations. The reduction of time of the disruption of the undertaking is vital in order to prevent a crisis. The seriousness of such a crisis usually grows exponentially and fast reaction and reduction of time to solve the problem is essential. The Continuity of Undertaking can help solve possible critical situation which may disrupt the activities of the transport companies. Furthermore, it can ameliorate possible consequences and efficiently smooth away possible aftermath of disruption of transport operation. The analysis and evaluation of BCMS is to strengthen the resilience of a transport company in order to better reach its key objectives.
Cell Behavior after Stimulation of Excess Gravity
Tamura, Takuya; Hino, Haruka; Hashimoto, Shigehiro; Sugimoto, Hiromi; Takahashi, Yusuke (Japan)
ABSTRACT:
The effects of the excess gravitational field on orientation and deformation of cells have been studied using centrifuge in vitro. Two kinds of cells were used in the test: C2C12 (mouse myoblast cell line), and Neuro-2a (mouse neural crest-derived cell line). To apply the mechanical force field (<100 G) to the cells adhered on the glass plate, the plate was set in the tube in a conventional centrifugal machine placed in an incubator (310 K, 5% CO2). The behavior of cells was traced at the time lapse images for 24 hours, after the excess gravitational stimulation for 1 or 5 hours. The contour of each cell was traced and approximated to ellipse to analyze the angle between the longitudinal axis of the cell and the direction of the excess gravity. The experiment shows following results. The longitudinal axis of C2C12 tends to align to the direction of the excess gravity, and turns to the perpendicular direction after stopping of the excess gravity. C2C12 aligns to the direction perpendicular against the excess gravity at division. The neurite of Neuro-2a extends along the direction of the excess gravity, and tends to extend subsequently apart from the excess gravity. The present study shows that the excess gravitational stimulation affects the behavior of cells after stimulation.
Clustering and Ranking Analysis with Imprecise Data for Evaluating Healthcare Performance of Districts in Istanbul
Karadayi, Melis Almula; Karsak, E. Ertugrul (Turkey)
ABSTRACT:
Over the past decade, healthcare has been one of the fastest growing sectors both in developed and developing countries. One of the main targets of most countries is to improve their healthcare system in terms of service quality and efficiency, where Turkey is no exception. This paper presents an imprecise data envelopment analysis (DEA)-based approach for clustering and ranking of 26 districts in Istanbul, the most crowded city of Turkey. The proposed methodology determines subgroups of districts operating under similar circumstances, and provides ranking of 26 districts as well as the best performing district in Istanbul in terms of healthcare utilizing data from state hospitals.
Coaching as a Facilitator of Organizational Sustainable Development in the Context of Life Cycle Theories
Rosha, Angelina; Lace, Natalja (Latvia)
ABSTRACT:
There has been much discussion over recent years about how organizations grow and what facilities their development. In the context of organization life cycle theories, the present paper aims to constitute the conceptual framework for the further research. The literature review on organization life cycle models and the issues of coaching as a support practice, with the specific emphasis on the indicators to measure results, are discussed. A five-stage organization life cycle models are analyzed and compared to detect contextual and structural
variables for the in-depth interview. The in-depth interview is designed for the managers who organize, monitor and are engaged in coaching programmes in
organizations, and aims to collect the data for the case study. The paper presents only the initial results of the interview, and therefore has certain limitations.
Communication and Narrative in the Construction of a Transdisciplinar Knowledge Base (Invited Paper)
López Caloca, Fernando; Parás Fernández, Margarita (Mexico)
ABSTRACT:
Transdisciplinar communication is an essential requirement for the successful implementation of projects that approach the complexity of socio-environmental problems we face in research and practice. Transdisciplinar knowledge integration can be achieved when conversations are built not only over common
principles, but also on how our spatial knowledge and experience is communicated over an issue in a specific territory.
Among the themes undertaken by interdisciplinary teams
are those related to territorial and land management,
ecosystem services, environmental risks and vulnerabilities, competitiveness, health, education, public safety, migration, water, energy, among other. This paper refers and expands the lessons learned through our line of research called Geomatics and Society and the transdisciplinar methodologies proposed for a Meta- Design for Geomatics applications (Paras-Lopez, 2017).
Specifically, we emphasize the role of the territory as a
connecting agent through the narratives of the interacting
stakeholders and experts, geared towards social needs or
problems and their possible solutions.
Our purpose is to approach the questions:
– ¿How to bring about the organization of
disciplines, their specialized models and
contributions to the solutions?
– ¿What principles and communication rules we
follow when an inter-disciplinary team works
together? – ¿Where to? Understand the dynamics of socioenvironmental organization in a specific time and place (the territory). Through interweaving the diverse knowledge and
territorial maps of experts with those of social claimants,
a transdisciplinar knowledge network emerges.
Conceptual Model and Instrument Reliability of Health Information Systems Effective Use by Health Practitioners
Adenuga, Olugbenga A.; Kekwaletswe, Ray M. (South Africa)
ABSTRACT:
In this study, we present a conceptual model for effective use of health information systems (HIS) by health practitioners in health care delivery. The study present a theoretical model underpinned by the unified theory of use and technology acceptance and the representation theory. The study survey 912 health practitioners working at various health facilities in Lagos state, Nigeria. The result shows present data collection instrument for the study. The outcome of the study also indicates the composite reliability the measurement instrument as the outcome is greater than the recommended reliability value of 0.7 or above for establishing reliability of the scale.
Contemporary Study Process for Enhancement of Employability in the Dynamic Environment
Lapina, Inga; Sceulovs, Deniss; Gaile-Sarkane, Elina; Dubickis, Mikus; Nikitina, Tatjana (Latvia)
ABSTRACT:
The requirements of labour market and the dynamic external environment are the competitive forces asking for a new employee competence – ability to align with the national and international labour market requirements. Routine tasks are progressively being replaced by technology therefore it is expected that in the nearest future there will be a greater need for such skills as independent problem-solving, planning, creative thinking, organisation and communication, even for basic jobs. Accordingly, serious changes are observed in the teaching, learning and assessment methods. The aim of the Paper is to reflect the results of three EU funded projects that were conducted to find out what skills and competences are required by modern labour market for current and future jobs, the problems encountered and the needs experienced in practice, and, finally, student perception about the modern teaching, learning and assessment methods.
Corrosion Simulation of High Stress Three Body Abrasion
Omer, Ako K. *; Chin, C. W. **; Yousif, B. F. ** (* Iraq, ** Australia)
ABSTRACT:
In this study, a numerical model was developed using ABAQUS software to study the corrosion behavior of stainless steel materials against epoxy composites. Effect of applied pressure and attacked particle angle on the high stress three body abrasion were studied. The simulation was made on newly developed epoxy composite based on kenaf fibres was fabricated and tested at high stress three body abrasion (3B-A). The damage features on the polymer and/or fibre regions was simulated. As results, both angle and applied pressure have significant influence on the breakage in the fibrous and resinous regions. 45o and high pressure caused higher damaged on both regions especially in the bonding area. When the fibre is parallel or antiparallel to the sliding directions, fracture in the fibre/epoxy regions predicted to be massive compared to another orientation when the fibre are normal to the sliding direction.
Coupling Functions between Brain Waves: Significance of Opened/Closed Eyes
Hussain, Lal; Aziz, Wajid; Saeed, Sharjil (Pakistan)
ABSTRACT:
In dynamical systems the information flows converges or diverges in state space and is integrated or communicated between different cells assemblies termed as CFC. This process allows different oscillatory systems to communicate in accurate time, control and distribute the information flows in cell assemblies. The CF interactions allow the oscillatory rhythms to communicate in accurate time, and reintegrate the separated information. The intrinsic brain dynamics in Electroencephalography (EEG) with eye - closed (EC) and eye open (EO) during resting states have been investigated to see the changes in brain complexity i.e. simple visual processing which are associated with increase in global dimension complexity. In order to study these changes in EEG, we have computed the coupling to see the inhibitory interneurons response and inter-regions functional connectivity differences between the eye conditions. We have investigated the fluctuations in EEG activities in low (delta, theta) and high (alpha) frequency brain oscillations. Coupling strength was estimated using Dynamic Bayesian inference approach which can effectively detect the phase connectivity subject to the noise within a network of time varying coupled phase oscillators. Using this approach, we have seen that delta-alpha and theta-alpha CFC are more dominant in resting state EEG and applicable to multivariate network oscillator. It shows that alpha phase was dominated by low frequency oscillations i.e. delta and theta. These different CFC help us to investigate complex neuronal brain dynamics at large scale networks. We observed the local interactions at high frequencies and global interactions at low frequencies. The alpha oscillations are generated from both posterior and anterior origins whereas the delta oscillations found at posterior regions.
Customized Learning Analytics: Six Prescriptive Steps
McKay, Elspeth; Barefah, Allaa (Australia)
ABSTRACT:
For various stakeholders across educational institutions, there is a broad awareness of data analytics. The way learning analytics is defined involves: providing assessment reports for individual learners to know how they rate compared with other learners; highlighting students who may need extra support; assisting teachers to plan supporting interventions for individuals and groups of learners; aids for professional development teams when considering new course design and development; and institutional/ corporate marketing and recruitment management strategies. However, for some people the practice of customized learning analytics may seem a daunting task. Using a prescriptive Learning Analytics Planning model, this paper will show why this perception is wrong. It is vital to understand the importance of validating the measurement tools; these steps describe the key processes that are necessary to carry out customized learning analytics through careful preparation of the testing instruments.
Deformation of Cell Passing through Micro Slit between Micro Ridges Fabricated by Photolithography Technique
Takahashi, Yusuke; Hashimoto, Shigehiro; Mizoi, Atsushi; Hino, Haruka (Japan)
ABSTRACT:
A micro slit has been designed between micro ridges, and deformation of a biological cell passing through the micro slit has been observed in vitro. The slit, of which width is 0.87 mm and height is 0.010 mm, has been made between the micro ridges on the transparent polydimethylsiloxane disk and glass disk by photolithography technique. The slit is placed at the middle part of a flow channel. Four kinds of cells were used in the experiment: C2C12 (mouse myoblast cells), HUVEC (human umbilical vein endothelial cells), Hepa1-6 (mouse hepatoma cells), and Neuro-2a (mouse neural crest-derived cells). The suspension of each kind of cells was injected to the slits. The deformation of cells passing through the micro slit was observed with an inverted phase-contrast microscope. The experimental results show that cells deform to the flat circular disk and pass through the micro slit of 0.010 mm height. The deformation ratio, the passing velocity, and the shape index of cells through the slit were evaluated: Hepa1-6 is deformed with the increase of the passing velocity, and HUVEC elongates along the flow. The designed slit between micro ridges has capability to evaluate the deformability of cells.
Discussion Note: Scientific Explanation of Complexity Systems
Sperry-Taylor, Ashton T. (United States)
ABSTRACT:
Complexity systems are composed of intractable webs of interacting components, and are unrepresentable at their micro-level. If explanation
of complexity systems is possible, it must be done with representations that accurately portray macrolevel phenomena. Equilibrium explanation is one
type of representation. Yet complexity systems are rarely in equilibrium, an empirical claim that impugns the utility of equilibrium explanation. I discuss the extent of which equilibrium explanations are false but still explanatory. Equilibrium explanations provide non-propositional understanding of phenomena by relating that phenomena to a consistent, comprehensive body of information. The result is that equilibrium explanations are examples of explanatory relations that are not factive. Nonetheless, they have value by
working in tandem with their parent sciences to generate novel hypotheses, and, ultimately, better veridical explanations.
Economic Impact of the Expansion of the Panama Canal in the US and Global Supply Chains
Lara Gracia, Marco A. (United States)
ABSTRACT:
After 34 years of extremely though construction work and extremely adverse working conditions, the Panama Canal started operations on August 15, 1914. More than $ 600 million were spent by France and the US to build the Canal. It is estimated that 80,000 persons worked during the construction project, 25,000 persons died during the same period of time, and that a total of 280,000,000 cubic yards of dirt were excavated and removed to build the Panama Canal. The economic impact of the Panama Canal in the US has been significant through the years. Approximately 68% of the tonnage that is transported in cargo vessels through the Panama Canal is originated in the US or bound for the US. More than 16% of the US total trade is transported through the Panama Canal. In 2006, the government of Panama announced the $ 5.2 billion expansion project of the Panama Canal to double its traffic capacity, which would be essentially achieved by building two new sets of locks (one on the Atlantic side and one at the Pacific side) bigger than the existing ones as well as deepening and widening the Canal in various points. On June 26, 2016, the containership COSCO made the inaugural passage of the expanded Panama Canal. This paper summarizes the history of the Panama Canal highlighting its economic impact in the US economy since the inaugural passage in 1914, describes the design and construction challenges and major milestones of the Canal expansion project, and includes a discussion regarding its impact in the Panama and US economies, global supply chains, and world trade.
Effect of Aspect Ratio of Checkered Convexo-Concave Micro-Pattern on Orientation of Cultured Single Cell
Sugimoto, Kenta; Takahashi, Yusuke; Hashimoto, Shigehiro; Hino, Haruka (Japan)
ABSTRACT:
The effect of the aspect ratio of checkered convexo-concave micro-pattern on orientation of the cultured single cell has been studied in vitro. The checkered convexo-concave pattern has been designed with micro quadrangular prisms in the square area of 1 mm × 1 mm on a disk of glass for a scaffold by the photolithography technique. Each prism has the following dimension: 0.01 mm length, and 0.0007 mm height. Variation has been made on the width of the prism: 0.005 mm, 0.008 mm, and 0.01 mm. The variation of the width makes the variation on the aspect ratio of the top rectangular surface of the prism: 1, 1.25, and 2. C2C12 (mouse myoblast cell line) were seeded on the micro pattern, and incubated for 24 hours in the Dulbecco’s Modified Eagle bovine serum and 1% penicillin/ streptomycin. The cells were observed with a phase contrast microscope. The experimental results show that the orientation of myoblast can be controlled by the aspect ratio of the checkered micro convexo-concave pattern of the surface of the scaffold.
Effect of Couette Type of Shear Flow by Rotating Disk on Migration of Cell
Sugimoto, Hiromi; Hino, Haruka; Hashimoto, Shigehiro; Takahashi, Yusuke (Japan)
ABSTRACT:
An experimental system with a rotating disk has been designed to apply wall shear stresses on the cell during incubation in Couette type of flow at the microscopic observation in vitro. The rotating disk system is mounted on the stage of an inverted phase contrast microscope to observe cells adhered on the plate under the shear flow (shear stress lower than 1.5 Pa). The migration of cells was evaluated at the time lapse images (every five minutes for 24 hours). The experiments on four kinds of cells show the following results. Under the shear flow (shear stress < 1.0 Pa), C2C12 (mouse myoblast cell line) migrates to the diagonal direction of the stream-line at 1.0 Pa, HUVEC (human umbilical vein endothelial cells) actively migrates at random at 1 Pa, 3T3-L1 (mouse fat precursor cells) migrates to the random direction, and L929 (fibroblast connective tissue) migrates in short distance. At 1.5 Pa, both C2C12 and HUVEC migrate to the downstream. The effect of shear flow on migration of the cell depends on kinds of cells. The designed system is useful to trace cells under the quantitatively controlled wall shear stresses.
Effect of Flow on Cultured Cell at Micro-Pattern of Ridge Lines
Hino, Haruka; Hashimoto, Shigehiro; Shinozaki, Yusuke; Sugimoto, Hiromi; Takahashi, Yusuke (Japan)
ABSTRACT:
A flow channel with a micro-pattern of ridge lines of a scaffold has been designed to study quantitatively the effect of flow on an oriented cell in vitro. The lines of parallel micro ridges (0.001 mm height, 0.003 mm width, and 0.003 mm interval) are made by the lithography technique on the lower surface of the channel as the scaffold to make orientation of each cell. Variation is made about the angle between the longitudinal direction of the ridge and the direction of the flow: zero, 0.79 and 1.6 rad. The suspension of C2C12 (mouse myoblast cell line) was injected to the channel, and incubated for two hours on the micro ridges before the flow test for four hours. The flow rate of < 36 cm3/hour is controlled by a syringe pump to make variation of the wall shear stress of < 3 Pa. The action of each cell adhered on the micro pattern was analyzed at the time lapse images. The experimental results show that both the migration and the deformation of each myoblast along the micro ridge are restricted by the wall shear stress higher than 3 Pa. The flow channel system with the micro pattern of ridge lines in vitro is effective to evaluate the effect of flow on cultured cells quantitatively.
Effect of Mechanical Property of Scaffold Surface with Micro Hybrid Striped Pattern on Cell Migration
Takahashi, Yusuke; Sugimoto, Kenta; Hashimoto, Shigehiro; Hino, Haruka (Japan)
ABSTRACT:
The effect of the mechanical property of the surface of the scaffold with the micro hybrid striped pattern on the migration of cells has been studied in vitro. The surface of the scaffold with the micro stripe pattern of bands (the width around 0.1 mm) was made by the photolithography technique. The variation of hardness of the surface of the band has been made of the materials alternately: polydimethylsiloxane (PDMS), and epoxy based negative photoresist material (SU-8). Three kinds of cells were used in the experiment: Neuro-2a (a mouse neural crest-derived cell line), L929 (fivroblast connective tissue of C3H mouse), and C2C12 (mouse myoblast). Cells were seeded on the micro pattern, and incubated for 24 hours in the medium. The total areas of cells at each band were evaluated at the microscopic images. The experimental result shows that most of cells migrate to the area of the band with SU-8, and that the tendency is considerable on L929. The experimental system is effective to investigate durotaxis of cells.
Efficient Frequent Pattern Mining of Big Data on a Distributed System
Shah, Syed Zubair Ahmad; Amjad, Mohammad; Habeeb, Ahmad Ali (India)
ABSTRACT:
With an exponential increase in the amount of data over the web and outside, data mining has become a burdensome task. Recently, researchers have turned to distributed systems for solving this problem. In this paper, we propose two algorithms to implement frequent pattern mining onto a distributed system. Both algorithms are applicable to small as well as very large datasets (big data). We have, theoretically, shown that our proposed algorithms will show better performance than using any traditional approach for frequent pattern mining.
Electric Measurement of Cultured Myoblast Oriented on Scaffold with Micro-Pattern
Hino, Haruka; Hashimoto, Shigehiro; Tamura, Takuya; Takahashi, Yusuke; Sugimoto, Tetsuya; Yasuda, Toshitaka (Japan)
ABSTRACT:
The electric impedance of cultured myoblasts oriented on the scaffold with micro pattern has been measured between surface electrodes in vitro. Several parallel lines of micro rectangular ridges (0.001 mm height, 0.003 mm width, and 0.003 mm interval) have been made between a pair of the surface titanium electrodes at the surface of the scaffold of glass by the photolithography technique. C2C12 (mouse myoblast cell line) was cultured for 4 days on the micro-patterned scaffold in the medium of D-MEM (Dulbecco’s Modified. Eagle Medium) The electric impedance between electrodes was measured once a day with the sinusoidal electric waves (frequency, 1 Hz < f < 1 MHz; amplitude, ±0.1 V < V1 < ±5 V). The experimental result shows that electric impedance has frequency characteristic and that the impedance of the capacitance component increases with proliferation of myoblasts. The orientation of myoblasts is detected by the impedance between the surface electrodes, when the orientation is varied by the direction of micro ridges of the scaffold.
Endothelial Cell Behavior After Stimulation of Shear Flow
Hashimoto, Shigehiro; Hino, Haruka; Sugimoto, Hiromi; Takahashi, Yusuke; Sato, Wataru (Japan)
ABSTRACT:
An experimental system of the Couette type flow with a rotating disk has been used to apply the wall shear stress quantitatively on the cell at the microscopic observation in vitro, and the behavior of the cell after stimulation of shear flow has been evaluated. The shear stress on the wall is calculated with an estimated Couette type of the velocity profile between the rotating disk and the stationary culture plate. Variation was made on the wall shear stress of 1.0 Pa and 1.4 Pa adjusted by the rotational speed of the disk. The rotating disk system is mounted on the stage of an inverted phase contrast microscope to observe the behavior of HUVEC (human umbilical vein endothelial cells) adhered on the plate after stimulation of the shear flow. Migration, deformation, and orientation of each cell have been traced at the time-laps image for 24 hours after the stimulation for 24 hours. The experiments show the following results. HUVEC tends to make orientation parallel to the stream line, and that the tendency is maintained for several hours. The migration of each cell is accelerated after stimulation of the wall shear stress of 1.4 Pa. The increase of area of each cell is decelerated by the higher wall shear stress. The Couette type of rotating disk system is effective to detect the behavior of cells after stimulation of the shear flow.
End-to-end Security with Translation (Invited Paper)
Foltz, Kevin E. (United States)
ABSTRACT:
End-to-end security involves two entities communicating at a distance over an insecure communication channel while maintaining many of the security properties of private, in-person communication. End-to-end security transforms an insecure channel into a secure one, such that the entities know who the other is, their communication is not interpretable by anyone observing the channel, and an active attacker that changes the content communicated will be detected. For digital communication it is desirable to have end-to-end security properties. However, not all entities that wish to communicate share a common language. This may be humans from different countries, web services that encode data in different formats, or applications that communicate with different protocols. The ideas they wish to share are common to both entities, but the representation of them is different. In such a case, end-to-end security limits the ability to use common translation methods that would allow communication. This paper discusses different translation approaches in the context of end-to-end security.
Environmental, Social, Governance and Economics Model of a Company's Sustainable Development as a Base for Investment Decision Making
Kocmanova, Alena *; Pavlakova Docekalova, Marie *; Lace, Natalja **; Nemecek, Petr * (* Czech Republic, ** Latvia)
ABSTRACT:
The paper presents the SEESG Model for sustainability assessment of companies using the composite indicator Corporate Sustainability Index (ICS), and their comparison in a case study. The composite indicator ICS is one of the options for constructing a benchmarking tool for comparing sustainability of companies in a given sector. The aim of this article is to compare manufacturing companies from different EU countries using the Sustainable Environmental, Social, Governance and Economics Model (SEESG Model) and a proposed composite indicator Index of Corporate Sustainability (ICS). The ICS integrates 16 economic and non-financial (environmental, social and corporate governance) performance indicators Iji, and is comprised of 5 sub-indices (economic sub-index ISEko1 Profitability; environmental sub-index ISEn1 Waste and Emissions and sub-index ISEn2 Resources consumption; social sub-index ISSoc2 Labour practices and Decent Work and corporate governance sub-index ISCg Monitoring and reporting corporate governance. Weights were determined by the PCA method. In the case study, six companies from the manufacturing industry from different countries were compared and the effectiveness of the composite indicator ICS in assessing sustainability was evaluated. Conclusions from the case study proved the suitability of the composite indicator ICS for comparing companies within the same industry, and for assessing corporate sustainability. For this reason, the SEESG Model for corporate sustainability assessment can be offered as a consistent and flexible model for investors. The use of the composite indicator ICS will make it possible for investors to integrate sustainability into their decision-making processes, achieve economic growth and help protect the environment as well as social values.
Eodataservice.org: Big Data Platform to Enable Multi-Disciplinary Intelligent Planet Applications via Informatics
Natali, Stefano; Mantovani, Simone; Folegani, Marco (Italy)
ABSTRACT:
We are currently living in a digital geospatial data world: everything is digitalized from the route we take to move, to the way we connect to the internet, weather information and so on. In this “digitalization of the living environment” artificial satellites have played a crucial role, and will play more in future: positioning, telecommunication, Earth observation – based services are directly or indirectly involved in all steps of our daily life. Talking about environmental monitoring, a revolution has happened in the last 20 years, moving from a limited number of observations (stations) and physical-based numerical models, to a massive data collection and supercomputing modeling with hybrid physical and statistical (machine learning) approaches. The various data sources, as well as simulated scenarios, feature, in most of the cases, different data formats, geographic and temporal representations, and this makes their simultaneous and combined exploitation difficult: enabling technologies are emerging to overcome the data access and combination issues. In this respect, the role of standardization is fundamental in both data representation and interfaces. The final scope is to make the data access steps “invisible” for the user, making the transition between data collections seamless, and allowing focusing on data visualization and analysis. This paper describes a multi-disciplinary geospatial data management platform that implements the full data lifecycle, allowing enhanced user experiences in both easiness of usage and completeness of the available functions.
Evaluating the Reusability of OLAPSec Framework: A Multilayer Security Framework for OLAP Systems
Altamimi, Ahmad Mousa; Al-Bashayreh, Mahmood Ghaleb (Jordan)
ABSTRACT:
Securing the access to Online Analytical Processing (OLAP) systems have become an increasingly important as such systems almost always house confidential and sensitive data that must be restricted to authorized users. A primary limitation of current security systems is that they are designed on top of a very specific data model. This can produce complex and error prone mappings to the elements of other OLAP systems. In addition, constructing comprehensive security systems that allow defining and associating security with an intuitive conceptual OLAP data model is a very complex process. To simplify the development process of security systems, one can consider the using of application frameworks. In this regards, many studies have been proposed frameworks to achieve the aforementioned goal. However, none of them has considered the reusability in its design or development process despite the fact that reusability is one of the main characteristics of successful application framework designs. Having said that, OLAPSec framework was developed to simplify the development process taking into account the reusability concept. This paper investigates the design of this framework in terms of the reusability evaluation method. To this end, empirical experiments have been conducted using well-known tools. Results showed that the framework design satisfies the reusability concept.
Evaluation of Banking System Monitoring: The Case of Russia
Svirina, Anna *; Syurkova, Sofia *; Semjonova, Nadezda **; Appalonova, Natalia *; Bazarov, Rustam * (* Russian Federation, ** Latvia)
ABSTRACT:
The paper evaluates Russian banking monitoring system after the creation of mega regulator on the basis of the Bank of Russia in 2013, when this authority combined both control and supervising functions in financial market. The study starts with testing of the two hypothesis using Bank of Russia dataset to assess the factors which are significant for banking operating risk evaluation. The testing of the stated hypothesis was performed by means of statistical analysis using SPSS Statistics 22.0. As the result of the study the hypothesis on factor estimation were rejected, and it was revealed that the Bank of Russia
is efficient for monitoring affiliated bank systems. To illustrate the findings we evaluate the case of 42nd largest bank in Russia for which the estimation of debt provided by the mega regulator was inaccurate, confirming existing
literature that major risk of single authority for control and supervising financial sector has the risk of overregulation with relevant decreasing monitoring and
control efficiency.
Fall Detection Based on Depth Image Sequence
Liao, Liangcan; Cao, Guitao; Cao, Wenming (China)
ABSTRACT:
Fall is one of the most signifcant causes of injury in the elderly. In this paper, we propose two types of feature extraction methods to detect when the fall happens based on the Kinect depth image sequences. One is assuming there exists different position lines in the XYZ 3-dimensional space, it will be active when the moving object touches it. The other is mapping the image sequences to single image by Speed-Time Depth Mapping (STDM), and obtain-ing the 36-dimensiona features in this image. The results of exper-imental demonstrate the effectiveness of our method.
From the Lab to the Field: 3D Technology Supporting Study and Conservation Processes on Ancient Egyptian Artefacts
Buscaglia, P. *; Biondi, E. *; Bovero, A. *; Quirino, T. ** (* Italy, ** Egypt)
ABSTRACT:
In this paper we will report on the importance of 3D documentation as a tool for study and communication in Cultural Heritage, with particular reference to the experience grown up at Centro Conservazione e Restauro La Venaria Reale (in the text: CCR La Venaria Reale) and to its application on Egyptian artefacts. We will focus on the purpose-built virtual viewer, set up in order to solve specific operational needs of the working group. We will consider for that significant case studies for innovation that 3D technology has brought in terms of streamlining processes and sharing results. We will also focus on technical advantages obtained by the realization of a 3D model of the remains of a 22nd dynasty cartonnage, found by the Italian Archaeological Mission at the area of the Temple of Millions of Years of Amenhotep II (Luxor, West bank, Egypt), and on the benefit in using 3D documentation on archaeological excavations.
Hacking a Bridge: An Exploratory Study of Compliance-Based Information Security Management in Banking Organization
Fagade, Tesleem; Tryfonas, Theo (United Kingdom)
ABSTRACT:
This work is approached through the lens of compliant security by drawing on the concepts of neutralization theory, a prominent postulation in the criminology domain and the ‘big five’ personality construct. This research is conducted based on a case study of ISO/IEC27001 Standard certified banks, to empirically evaluate the link between cyber security protocols violation and how employees rationalise security behaviour. We propose that compliance-based security has the propensity for a heightened sense of false security and vulnerability perception, by showing that systemic security violation in compliance-base security model can be explained by the level of linkages from the personality construct and the neutralization theory. Based on the survey responses from banking organization employees and the application of partial least square structural equation modelling (PLS-SME) analysis to test the hypothesis and validate survey samples, we can draw a strong inference to support the importance of individual security scenario effect as a vital complementary element of compliance-based security. We then suggest how information security can be addressed in that context.
How to Apply the User Profile Usability Technique in the User Modelling Activity for an Adaptive Food Recommendation System for People on Special Diets
Llerena, Lucrecia *; Rodríguez, Nancy *; Gómez-Abajo, Pablo *; Castro, John W. ** (* Spain, ** Chile)
ABSTRACT:
Interest among software professionals in the possibility of adapting software to user requirements has grown as a result of the evolution of software analysis, design and implementation thinking and the growth in the number of software systems users. Moving away from the traditional approach where the user has to settle for the options offered by software systems, different factors, like user needs, aspirations, preferences, knowledge level, goals and other distinguishing features, have to be taken into account for this purpose. Technically, this possibility is referred to as adaptiveness, and it requires user data. It is these data (user model) that determine the adaptiveness conditions. Our aim is to build a user model for adaptive systems applied to nutritional requirements, modelling user characteristics that affect their diets and help to improve their health. To build the user model, we apply the user profile usability technique. In order to validate our proposal, we analyse and design a preliminary prototype of an adaptive system capable of making food recommendations to satisfy specific user needs. This study revealed that diet is a propitious field for the development of adaptive systems and that user modelling is a good choice for design of this type of systems.
How to Measure the Efficiency of the Digital Marketing Channels?
Sceulovs, Deniss; Lorencs, Edvards (Latvia)
ABSTRACT:
According to estimates of various researchers, the total budget of the digital marketing channels will exceed the total budget of the traditional marketing channels as early as by 2020 [31]. Already in 2015 the digital marketing costs of the companies in the United Kingdom represented 40% of the total marketing costs [5]. Notwithstanding the rapid growth rate, level of awareness about the efficiency of the provided services is low, while there is no research on the characteristics of decision making on using particular digital marketing channels. Significant amount of practical information and research literature is not yet available owing the fact that the industry is newly formed and it grows rapidly. The industry grows so rapidly that by developing theoretical materials the included information might already be outdated, when it is published. For this reason the theoretical literature in this industry is related mainly to the general operating principles of the industry instruments and channels but the major part of the practical information and research literature focuses on the use of online tools. In addition to the obtained information authors express ideas that are based on their experience working with various digital marketing channels on a daily basis. The research described in this publication is the first research that has been performed in Latvia about the potential results that can be achieved using digital marketing channels. So far only research on the behaviour of the internet users in the internet environment in Latvia and on the purchase characteristic has been performed at the national level, while the results of research described in this publication are of practical relevance to the digital marketing sector companies as well as potential advertisers considering to use digital marketing channels.
Increasing the Attractiveness of Study Programs in the Field of Security and Safety
Sventekova, Eva; Holla, Katarina (Slovakia)
ABSTRACT:
The trend resulting from the unfavourable demographic curve from the university applicants point of view in Central Europe can be seen especially in the unfavourable numbers of the technical university applicants in Slovak republic. From the demographic point of view this adverse development should last during the next five years. The necessity to make the university study programmes aimed at the security services more attractive results from the current needs of the society and adverse trends of the security and safety situation development in Europe. The society needs to face the current threats inevitably and more effectively. Nowadays situation requires university-educated security and safety experts who have mastered the methods of solving the crisis phenomena and who are able to identify, analyse and assess the risks in various environments, to manage preventive activities and the adequate response to the crisis phenomena and to eliminate/reduce their negative consequences on people, material values and the environment. However, in the teaching plans of the secondary schools there are no subjects that would emphasise the need of the security and safety and protection of the society. The secondary school students are insufficiently motivated or informed about the possibilities of the university study in the sector of security and safety. This article describes the results of a pilot project realised at the Faculty of Security Engineering at The University of Zilina aimed at making the university study programmes in the area of security and safety more attractive by using innovative marketing tools. Essentially, results to be presented in article are coming out of two last years when new marketing strategy has been created and adopted on faculties’ departments.
Innovative Technique for Biotreatment of Phenol-Laden Wastewater Using Immobilized Mixed Cells
Ismail, Zainab Z.; Khudhair, Haneen A. (Iraq)
ABSTRACT:
Immobilization of growing microbial cells was considered as an innovative technique and effective in dealing with major environmental challenges for bioremediation of organics-loaded wastewater. This study was undertaken to
investigate the aerobic biodegradation of phenol at initial concentrations of 20, and 50 mg/L in petroleum refinery wastewater by using immobilized mixed cells (activated sludge) in spouted bed bioreactor. The mixed cells were immobilized in a polyvinyl alcohol-guar gum (PVA-GG) matrices. Immobilized mixed cells exhibited efficient phenol degradation in several successive reuse batches up
to 7 cycles without losing their degradation activity which could provide economic advantages when used in industrial-scale applications. Results of batch experiments in fluidized spouted bed bioreactor demonstrated that
complete removal of phenol using immobilized mixed cells in the first and second cycles was achieved after 90 min. The removal efficiency of phenol were 100%, 100%, 95%, 91%, 84%, 76%, and 70% for the 1st, 2nd, 3rd, 4th, 5th, 6th, and 7th cycles, respectively. Unlike the free cells, the potentiality of the immobilized cells is that they could be reused without reduction in their ability to degrade toxic phenols. Additional advantage of immobilized cells compared to free cells, is their ability to tolerate high concentrations of phenol.
Internal Medicine Residency Rotation Heuristic Scheduling Solution
Shaban, Sami; Al Marzooqi, Farida; Al Dhaheri, Mariam; Al Khamiri, Aysha; Al Eissaee, Shaikha (United Arab Emirates)
ABSTRACT:
An Internal Medicine residency heuristic scheduling algorithm was developed to help with scheduling of rotations. Requirements analysis was performed, the system was designed, developed, and then tested in a real-life environment. The system is now in use in an Internal Medicine Residency program.
IT Risk and Chaos Theory: Effect on the Performance of South African SMEs
Bayaga, Anass; Flowerday, Stephen; Cilliers, Liezel (South Africa)
ABSTRACT:
The purpose of the research was to investigate the relationship between information technology (IT) operations risk management (ORM) and small to medium enterprises’ (SMEs) performance. Following a review of the literature, a questionnaire was developed with the aim of addressing the research purpose. A simple random sampling technique was used to sample 107 respondents in a financial SME. In order to determine the percentage contribution of some of the identified significant predictors of challenges posed by ORM solutions, multiple regression analysis was used. The percentage distribution revealed that only one variable made a significant contribution: “The way in which end-users deal with the implementation of IT projects”. The results additionally revealed that the variable contributed approximately 88.4% of the variations in the level of variables that enhance SMEs’ performance. The analysis of variance also revealed that the regression coefficients were real and did not occur by chance. The recommendation of the study is that SMEs should improve the way they deal with the implementation of IT projects in order to address ORM.
Knowledge Sharing in Information Systems Development Projects: A Social Exchange Theory Perspective
Makhubele, Lean Mayana; Kekwaletswe, Ray (South Africa)
ABSTRACT:
The nature of information systems developments (ISD) projects requires various types of knowledge and experience from various project team members. ISD projects complexity makes it impossible for them to be accomplished by one individual and ISD projects are often staffed with individuals from various functional areas within the organization. Knowledge sharing amongst team members can be challenging since their backgrounds, expertise and context differs. In ISD projects, team members see their knowledge as their weapon for career advancement and find it difficult to willingly and actively share their knowledge and expertise with their fellow colleagues. Using Social Exchange (SET) theory as a lens, the purpose of this study was to explore and explain the factors that influence knowledge sharing in the context of information technology professionals during ISD projects in South Africa. The research model in this study was tested using Structural Equation Modeling (SEM) from data collected via a secure web survey of 180 Information technology professionals whose trade and practice is in information technology and or information systems in various industries of the South African economy. The results show that there is a positive relationship between interpersonal trust and knowledge sharing as well as knowledge sharing and individual performance.
Lexical Analysis of The Quran using Frequent Itemset Mining
Shah, Syed Zubair Ahmad; Amjad, Mohammad (India)
ABSTRACT:
This paper presents an analysis of the frequency of presence of words in different chapters of the Quran. It also presents an analysis of the repetition of verses in the Quran. For this purpose we have introduced a novel algorithm. Our research is based on a fundamental concept of frequent pattern mining: that, with regard to some collection of documents, the lexical frequency
profiles of individual documents are a good indicator of their conceptual content. The results obtained here show that the proposed approach produces results that are useful in getting onto the fundamental concepts of the Quran and can be of much help to the people of theology and to those who are interested in objective study of religious scriptures.
Measurement of Contractile Force of Myotube on Scaffold of Thin Film with Micro-Pattern-Markers
Takahashi, Yusuke; Hashimoto, Shigehiro; Sugimoto, Kenta; Watanabe, Daiki; Hino, Haruka (Japan)
ABSTRACT:
The scaffold of the transparent film with micro pattern markers has been designed to measure the contractile force of myotube under electric stimulation in vitro. The scaffold is made of a thin film (thickness 0.006 mm), of which the back side has arrangement of polydimethylsiloxane micro-protrusions (0.004 mm diameter, 0.002 mm height, interval 0.003 mm) made by the photolithography technique. C2C12 (mouse myoblast) was seeded on the film at the counter surface to the protrusions at the density of 50000 cells/cm2. The cells were cultured on the scaffold for 12 days in the medium containing 10% FBS (fetal bovine serum) and 1% penicillin/ streptomycin at 310 K with 5% of CO2 content. The electric pulses (amplitude of 30 V, 0.06 A); pulse cycle of 1 s; pulse width of 1 ms) were applied between electrodes of titanium wire dipped in the medium. The contraction of myotubes is able to be observed through the transparent scaffold at the microscope. The contractile force of myotube at the electric stimulation estimated by the deformation of the film was 10_4 N. The designed scaffold has a potential for the measurement of the local contractile force of myotube microscopically in vitro.
Measurement of Deformability of Biological Cell Passing through Single Micro Slit between Walls
Takahashi, Yusuke; Hashimoto, Shigehiro; Mizoi, Atsushi; Hino, Haruka; Yamaguchi, Takeshi; Yasuda, Toshitaka (Japan)
ABSTRACT:
A single micro slit has been designed between walls to observe the deformation of a cell passing through the slit in vitro. The micro slit of 0.015 mm width, 0.1 mm length and 0.05 mm height was fabricated between walls of weirs on the glass plate using the photolithography technique. The single micro slit is set in the flow path between parallel plates, of which dimension of the cross section has 2 mm width and 0.05 mm height. Three types of biological cells were used in the test alternatively: C2C12 (mouse myoblast cell line), Hepa1-6 (mouse hepatoma cell line), and Neuro-2a (mouse neural crest-derived cell line). The suspension of cells was introduced into the slits by the pressure difference between the inlet and the outlet, which was kept by the gravitational level of the medium. The cell passing through the slit was observed by the microscope. The movement and the shape of the cell was analyzed at the video images. The elastic modulus of myoblast passing through the slit estimated by the velocity (1 mm/s) and by the deformation ratio (0.5) of the cell in the slit was 10_ 2 Pa. The experimental results show that the designed slit has capability to measure deformability of the cell.
Measurement of Deformability of Cell by Slits between Micro Cylindrical Pillars
Takahashi, Yusuke; Hashimoto, Shigehiro; Hino, Haruka; Sugimoto, Hiromi (Japan)
ABSTRACT:
Deformation of a cell has been measured using slits between micro cylindrical pillars in vitro. Micro cylindrical pillars (0.02 mm diameter, 0.06 mm height) were fabricated on the glass plate using the photolithography technique. Variation was made on the gap between pillars: 0.025 mm, 0.020 mm, 0.015 mm, and 0.010 mm. The micro pillars were set in the flow path between parallel plates, of which dimension of the cross section has 1 mm width and 0.06 mm height. Two types of biological cells were used in the test alternatively: C2C12 (mouse myoblast cell line), Hepa1-6 (mouse hepatoma cell line). The suspension of cells was introduced into the slits, and the deformation of the cell at the slit was observed by the microscope. The experimental results show that several cells clogged in the slit of 0.01 mm, and the passing time of C2C12 is shorter than that of Hepa1-6 at the smaller deformation ratio. The designed slit has capability for evaluation of deformability of a cell.
Meeting Product Demand by an Imperfect EPQ-Based Model and an External Source
Chiu, Singa Wang; Chiu, Yuan-Shyi Peter; Liang, Gang-Ming; Chen, Yu-Ru; Li, Yi-Ying (Taiwan)
ABSTRACT:
This study considers meeting product demand by an imperfect economic production quantity (EPQ) model and an additional external source. Unlike the conventional EPQ model that assumes all products are of perfect quality and demand is satisfied by in-house fabrication, this paper examines an EPQ system with a random scrap rate and a portion of demand is met by an
external source in order to reduce in-house production loads. A mathematical model for this hybrid production decision system is developed and the long-run average system cost is derived accordingly. Optimization technique is used to determine the most economic in-house lot size for the system. Numerical example with sensitivity analyses is provided to show applicability of our research result.
Model Predictive Control of Building Heating Process Using Exponential Filtration in Harmonic Basis
Abdullin, Vildan; Shnayder, Dmitry; Kazarinov, Lev (Russian Federation)
ABSTRACT:
Advanced control techniques should be implemented to increase building heating process efficiency, as heating process is rather difficult for mathematical description and close-tolerance automatic regulation. Thus, a model predictive approach to the building heating process control is proposed. The core of the suggested control system is a model of building thermal performance inverse dynamics that is used as a predictive element. Since the perturbations that influence the building are periodic and expandable into a polyharmonic series, an exponential filter in the harmonic basis is used to build inverse dynamics model. An overall structure of the model predictive control system and main equations of its elements, as well as two different simplified models of building thermal performance, are presented and described. Viability of the proposed approach is confirmed by simulated example.
Multidisciplinary Learning Extends Communication Skill, and Helps Cross Cultural Understandings: Biomedical Engineering (Invited Paper)
Hashimoto, Shigehiro (Japan)
ABSTRACT:
Multidisciplinary learning has been discussed in relation to
cross-cultural understandings. "Biomedical engineering" is
exemplified for the multidisciplinary field, which includes biology, medicine, engineering, and others. Several learning programs have been practiced in the biomedical engineering field: in Japan, in Thailand, and in USA. Some of them are cross-cultural student-seminars on biomedical engineering. In the group work, students are divided into the small cross-cultural groups. Each group finds a problem, methods to solve the problem, and contribution to the society. Presentations are made with slides in reference to information in the internet. They have learned how to communicate with students, who has not only a variety of studying backgrounds but also a variety of cultural backgrounds. The training awakes students to several points: thinking from a different point of view, and using various communication tools. The process extends the communication skill, and helps cross-cultural understandings.
Myoblast Behavior around Surface Electrodes in Flow Channel
Takahashi, Yusuke; Hashimoto, Shigehiro; Yamauchi, Ryosuke; Hino, Haruka; Yasuda, Toshitaka (Japan)
ABSTRACT:
The behavior of biological cells around the surface electrode in the flow channel has been observed in vitro. The surface electrodes of titanium (thickness of 200 nm) are made along the edges of the flow channel by the photolithography technique. At the one of the edge, variations are made at the angle of the tip of each surface electrode: 0.26, 0.52, 0.79, or 1.0 rad at triangle or rectangle. The other edge is the reference electrode. One of three modes of cyclic electric stimulations (0.01 ms period) was applied between the surface electrodes: sinusoidal, pulse, or rectangular. Two kinds of cells were used in the test: porcine red blood cells, and C2C12 (mouse myoblast cell line originated with cross-striated muscle of C3H mouse). The suspension of cells was introduced to the flow channel, and the flow rate was controlled by the syringe pump. The experiment shows the following results. The movement of myoblasts changes by the electric stimulation through the surface electrodes during the flow along the channel. The movement depends on the tip angle of the electrode.
Natural Adsorbents and Mixed Oxides for Remediation of Oil or its Heavy Components
Acevedo Cortez, Javier S.; Oliva, Máximo; Kharisov, Boris I.; Serrano, Thelma; Kharissova, Oxana V. (Mexico)
ABSTRACT:
asphaltenes is imperative due to the importance of crude oil for many industries. Mixed oxides are proposed for the selective absorption of asphaltenes due to these organic molecules diminish the amount of oil extracted during the refining. Mixed oxides exhibit interesting interactions between their heteroatoms and the metallic atoms like Ni and Fe making possible to remove them from asphaltic cement and bitumen. Natural sorbents have some practical advantages for oil spill cleanup due to their cost, feasibility for real-life applications and environmental adaptability. In this work, adsorption capacity was determined
for lyophilized aloe, nopal and agar, which presented values of 9, 3 and 26 g of oil/g of sorbent, respectively. According SEM images the natural sorbents exhibit a 3D structure formed of biological materials, which form porous structure allowing the absorption of oil.
Non-Conventional Synthesis of Carbon Nano-Ribbons by the Low- Temperature Unfolding of MWCNTS
Kharissova, Oxana; Arquieta, Patsy; Solis, Andrés; Castillo, Alberto; Mendoza, Raquel (Mexico)
ABSTRACT:
In the present work, we have studied the treatment of multi-wall carbon nanotubes (MWCNTs) with the water-soluble cobalt octacarboxyphthalocyanine derivative theraphthal (TP, a cancer therapy drug) under ultrasonic conditions in the presence of ascorbic acid (AA) leading to the dispersion and unfolding of MWCNTs and production of ribbon-like nanostructures (NRs) at low temperatures. The synthesis was carried out using different amounts of slightly magnetic MWCNTs, AA and TP, which were ultrasonicated in 30 mL flasks with DI water for 1-6 h in ultrasonic cleaner at 42-45oC. In these conditions, even at low intensity ultrasound in cleaners (20-40 kHz), partial destruction of TP slowly takes place and it is known to be accompanied by formation of Reactive Oxygen Species (ROS). TP can be first coordinated to CNT surface via πΠ-stacking through aromatic supramolecular ring or covalently through COO- group(s) of the TP molecule. Unfolding of MWCNTs in the conditions of TP/AA addition can be explained by the in situ formation of ROS in TP solutions under ultrasonic treatment and their further attack on MWCNTs surface, destroying and unfolding them forming graphene sheets and ribbons. The obtained results differ from the conventional concepts of classic ππ-stacking interactions and/or σ-bonding between macrocycles and carbon nanotubes. Characterization of samples was made by Raman spectroscopy, Transmission Electron Microscopy (TEM) and IR-spectroscopy.
Online Exams as a Formative Learning Tool in Health Science Education
Park, Sang (United States)
ABSTRACT:
The purpose of the study was to evaluate the outcomes of the new online exam for the dental students to understand student study habits, performance, and satisfaction. A new form of assessment was implemented where students were allowed to take the online exam outside the classroom. The results showed that 51% strongly agreed or agreed that they prefer online exams to on-paper exams, and 38% strongly agreed or agreed that all exams should be converted to online delivery. Faculty also expressed interest in utilizing online assessments as opposed to the traditional on-paper exams. The introduction of an online exam program can offer another venue for promoting student learning as part of health science education.
Overview of Trends and Developments in Business Education
Nikitina, Tatjana; Lapina, Inga (Latvia)
ABSTRACT:
The aim of the research is to determine the latest trends and factors in the global external environment influencing the development and management of business education, as well as the impact of European Union policies on the transformation of business education. The research paper is developed on the basis of scientific publications review, using logical and comparative analysis methods. The essence of the research is to analyse the latest trends influencing business education development and management, as well as to summarize the findings and define the set of factors affecting the development of higher education institutions.
Policies, Legislation and Regulatory Compliance Governance Impact on Strategic Management of Higher Education and Research Institutions in Latvia
Straujuma, Anita; Lapina, Inga; Gaile-Sarkane, Elina; Ozolins, Modris (Latvia)
ABSTRACT:
Higher education and research institutions (HERI) are facing new challenges due to substantial changes in the business environment, as well as increasing regulatory impact by local and European Union (EU) legislation. Accordingly, strategic management process is becoming more complex. Regulatory compliance governance (RCG) as a holistic element of strategic management function is a relatively new phenomenon. It is even less discussed in research area of higher education and research management. The aim of the study and paper is to reveal how RCG functions are managed in HERI in Latvia and evaluate the role of RCG in strategic management of these institutions. The research is developed by applying the triangulation method. The theoretical background is formed on state of the art literature review. The authors perform field research on the impact of local and EU legislation, as well as higher education institutions strategic management paying particular attention to one part of it - regulatory compliance management. The results of research exposed the tools and extent to which local and EU legislation impacts HEI in Latvia. Further research can be performed to synthesize the most successful strategic management models that involve dedicated RCG resource on strategic decision level and strengthen competitive capabilities of HERI.
Predictive-Fixed Switching Frequency Technique for Six-Phase Wind Energy Conversion Systems
Rodas, Jorge; Gregor, Raúl; Ayala, Magno; González, Osvaldo (Paraguay)
ABSTRACT:
Considering the ongoing paradigm for the use of more renewable energy sources, wind energy conversion systems are considered mature technologies. The fault tolerance is one of the most sought-to capabilities for wind energy conversion systems. The ability to maintain operation even after an open-phase fault, allows the system operators to maintain energy production, presenting
tangible economic benefits, and the inherent redundancy of six-phase machines by providing the desired fault-tolerant capability with no extra hardware. As a result, different control schemes have been developed in the literature considering linear, non-linear and predictive structures. The latter, also known as finite-set model predictive control techniques are distinguished by a variable switching frequency which causes noise, large voltage and current ripples at low sampling frequency. This paper presents a speed control with an enhanced predictive current control technique with fixed switching frequency applied
to the six-phase wind energy conversion systems. Simulation results show the efficiency of the proposed technique, demonstrating that it is a viable alternative to conventional predictive controllers.
Proactive Maintenance Example of Selected Part of the Land Motor Vehicle
Furch, Jan; Stodola, Jiri (Czech Republic)
ABSTRACT:
This article deals with current trends in the maintenance of land vehicles. At present the system of preventive maintenance takes into account the technical condition of transport vehicles and equipment. The aim of the article is to show the possibilities of performing the preventive maintenance. This enables us to purchase new technical equipment. If we are to perform a condition based preventive maintenance, a vehicle has to be equipped with an on-board diagnostic system OBD-II and modern diagnostic instrumentation for individual types of technical equipment. Along with the technical aspects we should not forget about technical personnel training and interconnecting data within the information system. The aim of the work is to calculate the values of root mean square acceleration up to the moment a failure occurs. In the next step we will put the values into a graph and try to determine a gRMS limiting value. In the future this enables us to change the bearing before a failure occurs otherwise it would increase the related cost.
Provision of Technical Protection of the Railroads in Crisis Situations by the Private Construction Companies
Viskup, Pavel; Soušek, Radovan; Šustr, Martin (Czech Republic)
ABSTRACT:
After 1989 became changes in the Czechoslovakia (Czech Republic). The Crisis management in the railway transport can’t stay. In the recent years is a necessary new system for effectivity and economic profitability.
Qualitative Research with Social Workers in Diversion Programs in South Africa
Leclerc-Sherling, Christine (United States)
ABSTRACT:
This qualitative study was an exploratory step toward the creation of an instrument to measure positive peace as opposed to violence attitudes in organizations. Some of the benefits of this methodology were the co-construction of knowledge with the unit of analysis, where the behaviors and statements observed gave meaning only within the explanations that the population itself was giving to them. This process limited the ethnocentric biases and allowed for a more indigenous approach of constructive and innovative phenomenon in science and social systems.
Remote ECG Monitoring Kit to Predict Patient-Specific Heart Abnormalities
Chen, Jiaming; Razi, Abolfazl (United States)
ABSTRACT:
(ECG) signals are widely used to check heart rhythms and general health conditions using low-cost and relatively accurate equipment. However, the majority of commercial off-the-shelf ECG kits are generic and their normal ranges are set based on an average normal hearth signal hence ignorant of extreme variations among different people’s normal heart signals. As such, many false alarms are generated if the global thresholds are selected too strict. On the other hand, loosely selected thresholds may result in missing many true alarms. Furthermore, the kits output report typically includes a limited number of basic parameters such as heart rate and hence negligent to a rich set of information exploitable from signal morphology. In this paper, we developed a prototype for patient-specific heart monitoring kit, which learns the properties of a patient’s normal ECG signal over time and reports significant deviations from this normal behavior. In order to reduce the false alarm rate even further, the kit is equipped with an accelerometer in order to distinguish between high heart rates due to high physical activity levels and real abnormalities. This personalized remote heat monitoring kit with the proposed signal processing and self-tuning capabilities provides more detailed information and insightful interpretations compared to generic devices, therefore can be used for remote health monitoring of high-risk and elderly people.
Sмаrt City Evaluation Framework (SMACEF): Is a Smart City Solution Beneficial for Your City?
Lom, Michal; Pribyl, Ondrej (Czech Republic)
ABSTRACT:
There are currently presented ”smart city” solutions from the biggest worldwide corporation through start-ups up to the universities. It is indisputable that some of them are for sure very interesting and beneficial for citizens and cities
themselves. Nevertheless, there are too many provided solutions that make it very hard to evaluate which are really beneficial and which are not. A simple and understandable framework that would allow cities to evaluate a proposed smart city solution is currently missing. The aim of this paper is to provide an approach for evaluation of particular smart city solutions and to determine whether it is suitable and beneficial for the city. Cities are dynamic, non-linear, complex systems and the evaluation cannot be done by static and deterministic program
in most cases, but dynamics and non-linearity of cities must be considered. While modeling is widely used in transportation or energy management, in the field of smart cities, no modeling approach has been used. In this paper, SMACEF (SMArt City Evaluation Framework) is proposed and its contribution is
shown on a case study.
Steps Toward Quantifying Advancement in Space Exploration
Hall, Chelsea; Berleant, Daniel; Segall, Richard; Lu, Shen (United States)
ABSTRACT:
The purpose of this paper is to present a brief summary of preliminary research performed by the authors on project with objective of developing a group of simplistic models and metrics for measuring performance of success of projects of NASA. A starting point of this is to review related work by others for other
applications such as Moore’s Law for different types of advances in technology. The cover article (Denning & Lewis, 2017) of this year’s issue of Communications of ACM indicates that this is research of continuing interest.
Study of Race Condition: A Privilege Escalation Vulnerability
Farah, Tanjila; Shelim, Rashed; Zaman, Moniruz; Hassan, Md. Maruf; Alam, Delwar (Bangladesh)
ABSTRACT:
The Race condition is a privilege vulnerability that manipulates the small window of time between appliance of a security control and use of services in a system. This vulnerability is a result of interferences caused by multiple threads running in the system and sharing the same resources. These processes might include trusted process such as operating system files and untrusted processes. The race conditions vulnerability is one of the more common in UNIX-like systems, where directories /tmp and /var/tmp are shared between threads. A study of Race condition vulnerability is presented in this paper. Though Race condition could be found in various systems, this paper focuses on UNIX-like systems only.
Technopreneurial Development: Why Ecosystem Approach is Unsustainable in Case of Low Competition?
Svirina, Anna *; Syurkova, Sofia *; Laizans, Talis **; Appalonova, Natalia *; Bazarov, Rustam * (* Russian Federation, ** Latvia)
ABSTRACT:
The paper evaluates the influence of ecosystem development on technopreneurial activity rates by dividing this activity to the cases of high and low competitive environments. The study reveals that in case of low competition the soft factors, which come from entrepreneurial ecosystem and have significant positive influence on business development, do not have an important impact –and about ¾ of the impact are driven by hard entrepreneurial development factors which are not benefiting from entrepreneurial ecosystem development. The quantitative research presented in the paper indicates,
that different tools are necessary to foster technopreneurial development in the environments with low and high competition levels, and ecosystem approach
will be sustainable in case of relatively high level of competition. The testing of the stated hypothesis was performed by means of statistical analysis using SPSS Statistics 22.0.
The Distinction of Market Segments on the European 1520 mm Rail with Primarily Freight Transportation
Andins, Maris; Hudenko, Justina (Latvia)
ABSTRACT:
Article 32 (1) of Directive 2012/34/EU provides that in order to obtain full recovery of the costs incurred by the infrastructure manager (IM) a Member State may, if the market can bear this (MCB), levy mark-ups on the basis of efficient, transparent and non-discriminatory principles, while guaranteeing optimal competitiveness of rail market segments. The charging system shall respect the productivity increases achieved by railway undertakings (RUs). The main implementation problem is a question how to evaluate the MCB level, the productivity increases achieved by RUs and optimal competitiveness in an efficient, transparent and non-discriminatory way if: 1) the meanings of the included concepts are unclear for natural monopoly; 2) there are mutual contradictions among these concepts, for instance, obligation to allocate trains „which can pay at least the cost that is directly incurred as a result of operating the railway service…” and a commercial advantage to give priority to the most productive RU when capacity is limited; and 3) it is impossible to make unified methodology for mark-up evaluation due to the differences among EU rail markets. As a result of the study it was concluded that the distinction of market segments in networks with primarily freight transportation appears as a result of the requested deviations from the optimal usage of the rail network.
The Framework of Training Program of Paleobiology under the Background of Industry 4.0
Zhang, Yi; Cao, Cheng-Run; Zhu, Qun; Tang, Zhen (China)
ABSTRACT:
Each industrial revolution is triggered by new technique in that times, and afterwards gives a profound impact on research and education in each professional field. The development of Paleobiology also shows the process. In order to adapt to the rapidly changing world and gain an advantage in the competition, the design of new training program of Paleobiology should correspond to Industry 4.0 closely related to the forth industrial revolution, characterized as informatization and intellectualization. The practice in
College of Paleontology, Shenyang Normal University shows its necessity in the undergraduate education.
Unplanned Interdisciplinarity (Invited Paper)
Hendel, Russell Jay (United States)
ABSTRACT:
We explore three important examples of unplanned interdisciplinarity: i) Database theory, ii) definition of computable function, iii) the classification of groups. We show a commonality to each of the three examples. First, there is a silo stage where everyone works in their silo. This is followed by a mutual stage where the various silos discover mutual correspondences between their silos uncovering an unexpected commonality. Finally, this is climaxed by a stage of synergistic convergence where people reach a consensus agreeing on achieving a unified treatment.
With Reference to the ‘Mission to Mars’ Case Study, Galbraith’s Star Model and other Relevant Organization Theory, Critically Evaluate the Reorganization of the Mars Programme that Resulted from the Introduction of the ‘Faster, Better, Cheaper’ Approach a
Córdova G., Felisa; González A., Pablo (Chile)
ABSTRACT:
In the 1990s, NASA implemented a programme named "Faster, Better, Cheaper," (FBC) which involved essential changes to the way in which the organization used to be established. It was a huge organizational and transformational effort that required delivering dramatic advances in robustness, flexibility, and efficiency. Nevertheless in 1999, the failures of two consecutive Mars Climate Orbiter and Polar Lander missions brought to a stop of the FBC programme. We critically analyze and evaluate NASA’s reorganization across of two models of organization theory such as the Diamond and Star, which show that FBC style needed a super-high-tech, a high level of complexity and novelty, and a time-critical pace. In addition, the majority of the missions' failures were also because of the short schedule, limited budget, and a deficient coordination of the processes management particularly in learning.
Copyright © 2017 by International Institute of Informatics and Systemics
Published by International Institute of Informatics and Cybernetics